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L-Proline

(S)-Pyrrolidine-2-carboxylic acid · CAS 147-85-3

Intermediates Pharmaceutical intermediate / FCC CoA per lotSDSGMP statement

A cheap chiral pool entry point that shows up in asymmetric organocatalysis and in peptide side chains. Optical purity is the specification that matters; the racemisation is checked by chiral HPLC on every lot.

A chiral pool material. Optical purity is the release-critical attribute and is measured per lot, not per campaign.

Identity

Catalogue no.BP-INT-011
CAS number147-85-3
Molecular formulaC5H9NO2
Molecular weight115.13 g/mol
HS code2922.49
Synonyms(S)-Pyrrolidine-2-carboxylic acid
Product linePharmaceutical Intermediates
CategoryAmino Acids & Chiral Pool

Release specification

Catalogue standard below. For a supply agreement we release against your dossier specification; send it with the enquiry and the CoA will be built around it.

ParameterSpecification
Assay98.5–101.5%
Related substancesD-proline ≤ 0.20% (chiral HPLC); any unspecified impurity ≤ 0.30%
Water content≤ 0.5% (Karl Fischer)
Heavy metals≤ 20 ppm (ICP-MS)
Specific rotation[α]D20 −84° to −86° (c=4, water)
Residue on ignition≤ 0.10%

Application

Chiral pool starting material, organocatalyst precursor and cell-culture nutrient.

Packaging, storage & logistics

Standard packaging25 kg fibre drum with double PE liner
Minimum order25 kg
Lead time15–25 days
Storage conditionsStore below 30 °C in a dry place
Shipping documentsInvoice, packing list, CoA, SDS, certificate of origin; DGM/IATA declaration where applicable

Pack sizes available — pick one to prefill the enquiry

Documentation provided

  • CoA per lotLot-specific, with the test methods cited
  • SDSCurrent GHS revision; destination-language version on request
  • GMP statementSite-level GMP status and the last audit date, issued per customer

Need the DMF open part, a sample CoA or an audit pack before you can qualify us? Ask on the enquiry form — we send those documents before any commercial discussion.

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