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p-Toluenesulfonic Acid Monohydrate

PTSA monohydrate, Tosic acid, 4-methylbenzenesulfonic acid monohydrate · CAS 6192-52-5

Intermediates Technical / pharmaceutical intermediate CoA per batchSDSAssay by titrationSulphate statement

PTSA monohydrate is a workhorse acid catalyst, and the two failure modes in the plant are water content drift and sulphate carry-over. Both are on our CoA, and the material ships in a PE-lined drum that survives humid sea freight without caking.

Anhydrous PTSA (CAS 104-15-4) is available as a separate grade for routes that cannot tolerate the water of crystallisation.

Identity

Catalogue no.BP-INT-014
CAS number6192-52-5
Molecular formulaC7H8O3S · H2O
Molecular weight190.21 g/mol
HS code2904.10
SynonymsPTSA monohydrate, Tosic acid, 4-methylbenzenesulfonic acid monohydrate
Product linePharmaceutical Intermediates
CategoryAromatic Building Blocks

Release specification

Catalogue standard below. For a supply agreement we release against your dossier specification; send it with the enquiry and the CoA will be built around it.

ParameterSpecification
Purity≥ 98.5% (titration)
Related substancesSulphate ≤ 0.30%; water-insoluble matter ≤ 0.05%
Water contentWater 9.0–11.0% (monohydrate, Karl Fischer)
Melting range103–106 °C
ColourWhite, free-flowing
Anhydrous gradeCAS 104-15-4 available

Application

Acid catalyst for esterification, acetal formation and salt formation in API synthesis.

Packaging, storage & logistics

Standard packaging25 kg bag in fibre drum with PE liner; 25 kg HDPE pail
Minimum order500 kg
Lead time7–15 days
Storage conditionsStore in a dry place; material is hygroscopic and corrosive in solution
Shipping documentsInvoice, packing list, CoA, SDS, certificate of origin; DGM/IATA declaration where applicable

Pack sizes available — pick one to prefill the enquiry

100 g1 kg25 kg500 kg

Documentation provided

  • CoA per batchBatch-specific, tested against the specification agreed at PO stage
  • SDSCurrent GHS revision; destination-language version on request
  • Assay by titrationIssued with each lot on request.
  • Sulphate statementIssued with each lot on request.

Need the DMF open part, a sample CoA or an audit pack before you can qualify us? Ask on the enquiry form — we send those documents before any commercial discussion.

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